儿科药学杂志2013，Vol.19Issue(4)：41-45,5.
金茵清热口服液的制备及质量标准研究
Study on Preparation and Quality Standard of Jinyinqingre Oral Liquid
摘要
Abstract
Objective; To prepare Jinyinqingre oral liquid and establish its quality standard. Methods: The constituents such as rhubarb and astragalus in Jinyinqingre oral liquid were identified by TLC. The contents of chlorogenic acid, geniposide and salvianolic acid B in Jinyinqingre oral liquid were identified and determined by HPLC. Results; The characterisic spots in TLC were noted. The peaks of the three ingredients were segregated effectively. The linear range of chlorogenic acid was 6. 32 ~ 306. 60 μg/mL and the average recovery was 98. 72% , RSD= 1.30% . The linear range of geniposide was 12. 04~602. 00 μg/mL and the average recovery was 99. 43% , RSD = 0. 80% . The linear range of salvianolic acid B was 2. 668 ~ 133. 400 μg/mL and the average recovery was 95. 08% , RSD= 1.98% . Conclusions; This method is simple and reliable, and it can be used for the quality control of Jinyingqingre oral liquid.关键词
金茵清热口服液/薄层色谱法/高效液相色谱法/绿原酸/栀子苷/丹酚酸B/质量标准Key words
Jinyinqingre oral liquid/ TLC/ HPLC/ Chlorogenic acid/ Geniposide/ Salvianolic acid B/ Quality standard分类
医药卫生引用本文复制引用
郑江萍,庹芹,杜士明,黄良永..金茵清热口服液的制备及质量标准研究[J].儿科药学杂志,2013,19(4):41-45,5.
