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血小板活化状态在急性脑梗死中的意义及其与预后的相关性

姚平波 聂亚雄 赵红 张平

广东医学2013,Vol.34Issue(5):704-706,3.
广东医学2013,Vol.34Issue(5):704-706,3.

血小板活化状态在急性脑梗死中的意义及其与预后的相关性

The clinical significance of platelet glycoprotein in acute cerebral infarction

姚平波 1聂亚雄 1赵红 1张平1

作者信息

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摘要

Abstract

Objective To investigate of the prognostic significance of platelet glycoprotein ( GP ), Acute Physiology and Chronic Health Evaluation II ( APACHE II ) and acute Institute of Health Stroke Scale ( NIHSS ) in acute cerebral infarction ( ACI). Methods 68 patients with ACI and 48 health people were included in ACI group and control group, respectively. The ACI group was further divided into two subgroups, survival subgroup and non — survival subgroup, according to outcomes. GP, APACHE II and NIHSS were assessed. Results The levels of GP, APACHE II and NIHSS in ACI group were significantly higher than those in control group ( P < 0. 05 ); Furthermore, they were significantly lower in survival subgroup than in non — survival subgroup ( P < 0. 05 ). The GP was significantly positive correlated with APACHE II and NIHSS in patients with ACI. According to logistic regression analysis, GP, APACHE II and NIHSS were proved potential prognostic factors for patients with ACI. Conclusion GP, APACHE II and NIHSS can be important prognostic indexes for ACI.

关键词

血小板活化状态/急性脑梗死/预后

Key words

platelet activation/acute cerebral infarction/prognosis

引用本文复制引用

姚平波,聂亚雄,赵红,张平..血小板活化状态在急性脑梗死中的意义及其与预后的相关性[J].广东医学,2013,34(5):704-706,3.

基金项目

湖南省自然科学基金资助项目(编号:08JJ3036) (编号:08JJ3036)

广东医学

OA北大核心CSCDCSTPCD

1001-9448

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