河北医学2013,Vol.19Issue(5):685-687,3.DOI:10.3969/j.issn.1006-6233.2013.05.017
急性重症胆管炎外科治疗及相关指标与预后的关系
The Surgical Therapy of Acute Cholangitis of Severe Type and the Relation of Correlated Indices for Prognosis
摘要
Abstract
Objective: To observe the clinical situation of acute cholangitis of severe type and test the content of TNF-α,IL-1 and LI-6 which in different period before and after operation,analyze the important of performing ACST operation promptly and the indication of correlated indices for prognosis. Method: Selected 42 ACST patients accepted operation , analysed their clinical data and modus operandi ; and divided into cure group and null group by therapeutic efficacy, detect the content of TNF-α, IL-1 and LI-6 in patients serum respectively , selected 30 healthy volunteers as a control group. Result: The content of TNF-α, IL-1 and LI-6 in 42 ACST patients during operation were higher than the control group, There's remarkable significance (P<0.05),the content of TNF-a and IL-1 in cure group after operation 7 days were lower than the null group, There's no remarkable significance (P>0. 05),but the content of LI-6 was higher than the null group have remarkable significance (P<0.05); the content of TNF-α,IL-1 and LI-6 in cure group after operation 14 days were lower than the null group, have remarkable significance (P<0.01). Conclusion: Early diagnosis and appropriate treatment is key point for success of ACST operation, the test of TNF-α,IL-1 and LI-6 in serum has important index effect for the diagnose and prognosis of ACST.关键词
急性重症胆管炎/外科治疗/预后Key words
Acute cholangitis of severe type/ Surgical therapy/ Prognosis引用本文复制引用
陈龙林,连秋宜,黄子林..急性重症胆管炎外科治疗及相关指标与预后的关系[J].河北医学,2013,19(5):685-687,3.