家畜生态学报2013,Vol.34Issue(1):73-77,5.
MicroRNA与哺乳动物的性腺发育
MicroRNA and Gonadal Development in Mammals
摘要
Abstract
MicroRNAs(miRNAs), a class of noncoding RNA of approximately 21-24 nucleotides in length, play a role in post-transcriptional regulation of target gene expression by cutting the transcript of target genes or inhibit the translation of the transcript. It was found that miRNA can regulate the development of ovarian and testicular, and promote the maturation of oocytes and the differentiation of sperm, which has an extremely close relationship with gonadal development of mammals. This paper reviewed miRNAs' biogenesis, mechanism of action and its regulation in mammals gonadal development.关键词
MicroRNA/哺乳动物/性腺/发育Key words
microRNA/ mammals/ gonadal/ development分类
农业科技引用本文复制引用
向浩,张晓东,凌英会,丁建平,章孝荣..MicroRNA与哺乳动物的性腺发育[J].家畜生态学报,2013,34(1):73-77,5.基金项目
国家高技术研究发展计划(863)计划项目(2011AA100307) (863)
安徽省科技计划项目(11010302108) (11010302108)