基础医学与临床2013,Vol.33Issue(3):370-373,4.
TRPM家族对细胞钙/镁平衡调控的研究进展
Recent advances in the study of regulation effect of TRPM family in cellular calcium/magnesium homeostasis
摘要
Abstract
Melastatin-related transient receptor potential (TRPM) channels are members of the transient receptor potential (TRP) channel superfamily. All the members are permeable to Ca2+ and Mg2+ except TRPM4 and TR-PM5. TRPM1, TRPM2, TRPM3 and TRPM8 are regulators of Ca2+ and magnesium homeostasis, TRPM6 and TRPM7 are key regulators of Mg2+ homeostasis. TRPM channels are widely distributed and activated by a variety of stionulation. They play a fundmental role in regulating cellular calcium / magnesium homeostasis and other various cell biological processes.关键词
TRPM阳离子通道/钙离子平衡/镁离子平衡Key words
TRPM cation channels/ calcium homeostasis/ magnesium homeostasis分类
医药卫生引用本文复制引用
张厉,杨春喜,贺石生..TRPM家族对细胞钙/镁平衡调控的研究进展[J].基础医学与临床,2013,33(3):370-373,4.基金项目
国家自然科学基金(81101344/H0604) (81101344/H0604)
同济大学附属第十人民医院优秀青年人才培养计划(11RQ104) (11RQ104)