兰州大学学报(医学版)2013,Vol.39Issue(1):27-29,3.
育龄期与围绝经期女性血清性激素水平与骨钙素的关系
Relation of reproductive hormones and serum osteocalcin with perimenopausal and child-bearing women
摘要
Abstract
Objective To evaluate the practical value of serum N-mid osteocalcin (N-midBGP) and follicle-stimulating hormone (FSH), luteinizing hormone, estradiol Ⅱ on the bone metabolism in perimenopausal women. Methods Serum levels of FSH, luteinizing hormone, estradiol Ⅱ and N-midBGP were detected in 130 cases of perimenopausal women (study group) and 60 cases of normal fertile group (control group) by using electrochemiluminescence method. Results There was significant difference in serum levels of FSH, luteinizing hormone, estradiol Ⅱ , N-midBGP for the two groups (P <0.01). Correlation analysis showed that while serum levels of FSH, luteinizing hormone, N-midBGP increased the serum level of estradiol Ⅱ decreased in the perimenopausal women. Conclusion Detecting the changes of serum osteocalcin and reproductive hormone levels has an important value for early prevention, diagnosis and treatment the osteoporosis in perimenopausal women.关键词
围绝经期妇女/骨钙素N端中分子片段/性激素/骨代谢异常Key words
perimenopausal women/ N-mid osteocalcin/ reproductive hormones/ abnormal bone metabolism分类
医药卫生引用本文复制引用
宋霞,刘纯,孙晶晶,刘亚丽..育龄期与围绝经期女性血清性激素水平与骨钙素的关系[J].兰州大学学报(医学版),2013,39(1):27-29,3.