南京医科大学学报（自然科学版）2013，Vol.33Issue(2)：235-238,4.DOI:10.7655/NYDXBNS20130220
脐血浆中硫化氢与分娩宫缩发动关系的探讨
The relationship of hydrogen sulfide in cord plasma and the contraction of myometrium
摘要
Abstract
Objective;To explore the relationship between endogenous hydrogen suliide (H2S)of the blood plasma and the contraction of myometrium. Methods:The sixty cord plasma samples were collected and divided into two groups according to the delivery has not launched the contractions. The concentration of H2S was assayed by sensitive sulphur electrode. The expressions of cystathionine beta-synthase(CBS) and cystathionine gamma-lyase (CSE) in placenta were measured by using immunohistochemistry. Results; H2S contents in the group which mothers did not start uterine contraction were higher than that mother started uterine contraction (P=0.01); The expressions of CSE were detected in cytoplasm of placental villi trophoblast cells and at higher levels in the group with mothers did not start uterine contraction. The expressions of CBS had not seen in both two groups. Conclusion: Cytoplasm of placental villi trophoblast cells are included CSE and no CBS. The production of H2S in cord plasma is regulated by trophoblast cells. H2S content in cord placenta is related to initiation of parturition.关键词
硫化氢/子宫平滑肌细胞/分娩/脐血浆/免疫组化Key words
hydrogen sulfide/uterine smooth musle cell/parturition/cord plasma/immuno-histochemistry分类
医药卫生引用本文复制引用
张涛,董淑君,张雪莉,庄宝祥,刘红丽,张圣明..脐血浆中硫化氢与分娩宫缩发动关系的探讨[J].南京医科大学学报（自然科学版）,2013,33(2):235-238,4.基金项目
潍坊市科技局资助(20112033) （20112033）
