青岛大学医学院学报2013,Vol.49Issue(1):38-40,43,4.DOI:10.11712/qdyxy201301014
海德堡OCT测量后极部视网膜厚度对青光眼诊断价值
THE DIAGNOSTIC VALUE OF MEASUREMENT OF POSTERIOR POLE RETINAL THICKNESS WITH HEIDELBERG OCT IN GLAUCOMA
摘要
Abstract
Objective To observe the posterior pole retinal thickness of normal and glaucoma measured by optical coherence tomognaphy (OCT), and evaluate its value in the diagnosis of glaucoma. Methods The thickness of posterior pole retina of 40 normal cases (40 eyes) and 41 glaucoma (64 eyes, including 53 POAG and 11 PACG) were respectively measured by Heidelberg Spectralis OCT. The image features of posterior pole retinal mapping in normal individuals and patients with glaucoma were observed and compared, the correlation between MD and retinal thickness was calculated as well. Results The posterior pole retinal mapping in normal persons appeared as U-shaped, and that shape was not typical or disappeared in glaucoma. There was no statistical difference among the thickness of posterior pole retinal in average, superior and inferior in health adult group (F = 0. 800,P>0. 05) , in patients with glaucoma, the thickness of posterior pole retinal was thinner than that in normal group (F = 59. 569 — 72. 364,P<0. 01) ; the same finding was also appeared in early glaucoma (t = 2. 828,P<0. 01). The posterior pole retinal thickness in glaucoma was negatively correlated with MD (r= —0. 619,P<0. 01). Conclusion In glaucoma, the changes of thickness of posterior pole retina have a close correlation with changes of function of visual field, and appear earlier than defect of visual field, which is likely to be a marker to replace detection of retinal ganglion cell loss.关键词
体层摄影术,光学相干/青光眼/视网膜/视野Key words
tomography, optical coherence/ glaucoma/ retina/ visual fields分类
医药卫生引用本文复制引用
邢业娇,王大博,纪珍,刘鹏辉..海德堡OCT测量后极部视网膜厚度对青光眼诊断价值[J].青岛大学医学院学报,2013,49(1):38-40,43,4.