陕西医学杂志2013，Vol.42Issue(4)：409-411,3.
不稳定型心绞痛患者外周血内皮祖细胞与冠状动脉狭窄程度的关系
Correlation between endothelial progenitor cells from peripheral blood and coronary artery stenosis in patients with unstable angina
摘要
Abstract
Objectives: To investigate the correlation between endothelial progenitor cells(EPCs) from peripheral blood and coronary artery stenosis in patients with unstable angina(UA). Methods: Eighty patients were divided into UA group(n=53) and control group(n = 33). The number of circulating CD34+/CD133+ of peripheral blood mononuclear cells(PBMCs) from two groups were counted by flow cytometry at the time of admission. Severity of coronary stenosis was assessed with the Gensini scoring system. Then investigate the correlation between the number of EPCs from peripheral blood and coronary artery stenosis. Results:The number of EPCs was significantly reduced in patients with UA campared with control group. And compared to the slight coronary artery srenosis(P＜ 0. 05), the number in serious stenosis was increased(P＜0. 05). The degree of coronary artery stenosis is direct correlation with the number of EPCs(P＜0. 05). Conclusion:The number of EPCs was significantly reduced in patients with UA. But serious coronary artery stenosis can increase the number of endothelial progenitor cells.关键词
心绞痛,不稳定型/病理生理学/内皮祖细胞/冠状动脉狭窄Key words
Angina, unstable/physiopathology/ @Endothelial progenieor cells/ Coronary stenosis分类
医药卫生引用本文复制引用
陈杰民,涂昌,梁逸仙,兰军,陈本发,刘映峰..不稳定型心绞痛患者外周血内皮祖细胞与冠状动脉狭窄程度的关系[J].陕西医学杂志,2013,42(4):409-411,3.基金项目
广东省医学科研基金(A2011722) （A2011722）
