生殖医学杂志2013，Vol.22Issue(2)：114-118,5.DOI:10.3969/j.issn.1004-3845.2013.02.008
多囊卵巢综合征患者静息心率与糖脂代谢及血压等指标关系的研究
Relationship among resting heart rate, glycolipid metabolism and blood pressure in patients with polycystic ovary syndrome
摘要
Abstract
Objective: To investigate the relationship among resting heart rate, glycolipid metabolism and blood pressure in patients with polycystic ovary syndrome(PCOS). Methods: Seventy seven patients with PCOS and seventy three healthy women volunteers as control were enrolled in the study in Department of Reproductive, Navy General Hospital from August 2011 to June 2012. The two groups were divided to four subgroups according to obese or non-obese. The serum levels of lipids, fasting blood glucose, blood glucose after meal, fasting insulin and insulin after meal were measured. The body weight, blood pressure and resting heart rate were calculated. Independent-samples t-test and partial correlation analysis were used to evaluate the relationship between resting heart rate and cardiovascular risk factors in patients with PCOS. Results: (1)The resting heart rate [(82. 09±7. 86)/min vs. (79. 55±5. 66)/min], body mass index (BMI), blood pressure, blood glucose and insulin in PCOS group were significantly higher than those in control(P<0. 05). (2) The resting heart rate was significantly correlated with BMI, systolic pressure, fasting insulin, insulin after 1 hour meal, and triglyceride (r = 0. 177, 0.191, 0.199, 0.204, 0.216 respectively, all P<0, 05). (3)The resting heart rate, systolic pressure, lipids and blood glucose after 1 hour in non-obese subgroup of PCOS were significantly higher than those in obese group of control. (4) After exclusion of confounding factors, such as BMI, diastolic pressure, fasting blood glucose and fasting insulin, the increase of systolic pressure (β=0. 237) and triglyceride level(β=0. 222) was independent risk factors for resting heart rate(P<0. 05) by multivariate linear regression analysis. Conclusions: The study indicates that increase of resting heart rate in PCOS patient is associated with increase of systolic pressure and triglyceride level. The resting heart rate in PCOS group is higher than that in control group along with increase of systolic pressure and triglyceride level.关键词
多囊卵巢综合征/静息心率/血压/血脂/血糖Key words
Polycystic ovarian syndrome/ Resting heart rate/ Blood pressure/ Lipid/ Blood glucose引用本文复制引用
裴友娟,王蔼明,闫玲,李敏..多囊卵巢综合征患者静息心率与糖脂代谢及血压等指标关系的研究[J].生殖医学杂志,2013,22(2):114-118,5.基金项目
军队"十一五"科技攻关课题(06G006) （06G006）
