天然产物研究与开发2013，Vol.25Issue(2)：161-165,5.
水飞蓟宾乳糖苷的合成、表征及抗氧化活性研究
Synthesis, Characterization and Antioxidant Activity of Silybin Lactosified Derivatives
摘要
Abstract
To improve the solubility and biological activity of silybin,silybin lactosified derivatives were synthesized with silybin and lactose. The targeted compounds were characterized by IR.1H NMR,13C NMR and HPLC-MS,respectively. Reducing power,DPPH.ABTS+ radical scavenging assays and determination of lipid peroxidation were carried out to e-valuate the antioxidant and free radical scavenging abilities of silybin and its lactosified derivatives. The results showed that the antioxidant and free radical scavenging abilities of lactoside silybin was stronger than those of silybin.关键词
水飞蓟宾/乳糖苷/水溶性/合成/抗氧化Key words
silybin/lactoside/solubility/synthesis/antioxidant activity分类
医药卫生引用本文复制引用
汪艳丽,余燕影,曹树稳..水飞蓟宾乳糖苷的合成、表征及抗氧化活性研究[J].天然产物研究与开发,2013,25(2):161-165,5.基金项目
国家自然科学基金项目(20962014) （20962014）
