武汉工程大学学报2013，Vol.35Issue(2)：28-31,4.DOI:10.3969/j.issn.1674-2869.2013.02.006
荩草的化学成分
Chemical constituents of Arthraxon hispidus (Thunb) Makino
摘要
Abstract
Arthraxon hispidus is rich in resources and has a long medication history. In order to find the active ingredient and enrich the types of compounds, the system study on its chemical constituents was carried out. The chemical constituents of A. hispidus were extracted by 80% ethanol. The residue was suspended in water and then extracted successively with Petroleum ether, chloroform, ethyl acetate and n-butanol. Chloroform part and ethyl acetate part were isolated and purified by silica gel column chromatography and recrystallization. Their structures were characterized by chromogenic reaction, ultravioet, infrared, mass spectrometry, 1H and 13 C nuclear magnetic resonance and 2 D nuclear magnetic resonance experiments such as Distortionless Enhanced by Polarization Transfer, Heteronuclear Muliple Boan Correlation and Heteronuclear Single Boan Correlation. Ten compounds including 3,5,7-trihydroxy-3' ,5 '-dimethoxylflavone (1), dehydrocorydaline (2), Stigmasterol-3-0-β-D-glucoside (3), n-Tetradecane (4), n-Pentadecane (5), n-Octadecane (6), n-Nonadecane (7), n-Docosane (8), n-Tetracosane (9), n-Pentacosane (10) were isolated and identified. Among these ten compounds, compounds 1—3 are obtained from this plant for the first time.关键词
荩草/化学成分/分离纯化/3,5,7-三羟基-3',5'-二甲氧基黄酮/去氢紫堇碱Key words
Arthraxon hispidus (Thunb) Makino/ chemical constituents/ separation and purification/ 3,5,7-trihydroxy-3 ,5-dimethoxylflavone/ dehydrocorydaline分类
医药卫生引用本文复制引用
肖艳华,李彦超,帅维,曹辉,高婷..荩草的化学成分[J].武汉工程大学学报,2013,35(2):28-31,4.基金项目
湖北省教育厅优秀中青年人才科研项目(Q20091509) （Q20091509）
武汉工程大学研究生创新基金(CX201105) （CX201105）
