西北国防医学杂志2013，Vol.34Issue(2)：140-143,4.
实时组织弹性成像与肝纤维化指标联合诊断肝纤维化的研究
Combined detection of real-time tissue elastography and indicators of hepatic fibrosis in diagnosing hepatic fibrosis
摘要
Abstract
Objective: To observe the clinical value of real - time tissue elastography ( RTE) and indicators of hepatic fibrosis (HA, LN and IV - C) in diagnosing hepatic fibrosis in chronic hepatitis patients. Methods: Twenty - nine patients with chronic hepatitis, 27 patients with cirrhosis and 25 who took physical examinations were enrolled. RTE was performed and indicators of hepatic fibrosis were measured by ELISA. Results: Thirty - six patients were RTE positive, 20 were RTE negative. The sensitivity, specificity and the accuracy rate of RTE for diagnosing hepatic fibrosis was 96. 30% (26/27), 65.52% (19/29), 80.36% (45/56) respectively, the indicators of hepatic fibrosis (HA, LN and IV - C) were apparently increased in both chronic hepatitis group and cirrhosis group(P <0. 01 ) compared with normal controls group. With the development of hepatic disease, the levels of HA and IV - C in cirrhosis group were apparently increased than that of in hepatitis group (P <0. 05). Conclusion: RTE is a new and promising sonography - based noninvasive method for the assessment of hepatic fibrosis in patients with chronic hepatitis B. The combined detection of RTE and indicators of hepatic fibrosis (HA, LN and IV -C) have great clinical significance in diagnosing hepatic fibrosis in chronic hepatitis patients, which can prognosticate the development of hepatic pathological change.关键词
肝硬化/肝纤维化/弹性成像技术/慢性肝炎Key words
Liver cirrhosis/ Hepatic fibrosis/ Elasticity imaging techniques/ Chronic hepatitis分类
医药卫生引用本文复制引用
郭玲,焦建中,赵夏夏,周小平..实时组织弹性成像与肝纤维化指标联合诊断肝纤维化的研究[J].西北国防医学杂志,2013,34(2):140-143,4.
