西南国防医药2013，Vol.23Issue(4)：372-374,3.DOI:10.3969/j.issn.1004-0188.2013.04.009
老年重症肺炎行机械通气患者病原菌分布及耐药率分析
Distribution of pathogenic bacteria and drug resistance in senile patients with severe pneumonia receiving mechanical ventilation
陆卫华 1杨剑虹 1方庆 1李刚 1唐忠志1
作者信息
摘要
Abstract
Objective To discuss the distribution of pathogenic bacteria and the drug resistance in senile patients with severe pneumonia who received mechanical ventilation, and to provide references for clinical reasonable use of antibiotics. Methods The sputum specimens were obtained by bronchoscope. Detection was made in the pathogenic bacteria and their drug resistance in 108 senile patients with severe pneumonia who received mechanical ventilation. Results Among the 108 cases, the positive rate of germiculture was 81. 50%. There were totally 92 strains of bacteria detected, among which 68 strains were G- bacillus( 73. 90% ), including klebsiella pneumonias ( 25. 00% ), pseudomonas aeruginosa( 19. 60% ), acinetobacter baumannii( 13. 00% ), enterobacter cloacae ( 6. 50% ) ,escherichia colt 4. 30% ). There were 14 strains of fungi( 15. 20% )and 10 strains of G+ bacillus( 10. 90% ). G- bacillus had lower drug resistance rate to polymyxin, imipenem, biapenem, and piperacillin/ tazobactam. The G+ bacillus had lower drug resistance to vancocin, teicoplanin, and fusidic acid. The drug resistance rates of fungi were all lower than 30. 00% . Conclusion For senile patients with severe pneumonia receiving mechanical ventilation,the main pathogenic bacterium is G~ bacillus,and the next were fungi and G+ bacillus. The drug resistance rate of G- bacillus and G+ bacillus is higher,and that of fungi is lower.关键词
老年/重症肺炎/机械通气/病原菌/耐药Key words
senile/ severe pneumonia/ mechanical ventilation/ pathogenic bacteria/ drug resistance分类
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陆卫华,杨剑虹,方庆,李刚,唐忠志..老年重症肺炎行机械通气患者病原菌分布及耐药率分析[J].西南国防医药,2013,23(4):372-374,3.
