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皂角刺提取物体外抑菌杀菌作用研究

刘建建 时鹏 黄涛 张凯 吴大畅

医药导报2013,Vol.32Issue(3):300-302,3.
医药导报2013,Vol.32Issue(3):300-302,3.DOI:10.3870/yydb.2013.03.008

皂角刺提取物体外抑菌杀菌作用研究

in Vitro Bacteriostatic and Bactericidal Activities of Extracts from Chinese Honeylocust Spine

刘建建 1时鹏 1黄涛 1张凯 1吴大畅1

作者信息

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摘要

Abstract

Objective To explore bacteriostatic and bactericidal activities of Chinese Honeylocust Spine extracts against common laboratory bacteria (Escherwhia coli, Bacillus subtilis, Staphylococcus aureus, Candida albicans, Pseudomonas aerugino-sa) . Methods Extracts from Chinese Honeylocust Spine were prepared with different solvents at various concentrations. The activities and minimum inhibitory concentration (MIC) were tested with filter paper and double dilution methods. Results The extracts from Chinese Honeylocust Spine had little bacteriostatic or bactericidal effect against E. coli, Bacillus subtilis, Candida albicans, and Pseudomonas aeruginosa, but they showed moderate effects on Staphylococcus aureus. The MIC of water and ethanol extracts against Staphylococcus aureus was 25.0 and 12. 5 mg· mL-1, respectively. Conclusion Extracts from Chinese Honeylocust Spine have both bacteriostatic and bactericidal actions against Staphylococcus aureus.

关键词

皂角刺提取物/抑菌作用/杀菌作用/最低抑菌浓度

Key words

Extracts of Chinese Honeylocust Spine/ Bacteriostasis/ Bactericidal effects/ Minimum inhibition concentration

分类

医药卫生

引用本文复制引用

刘建建,时鹏,黄涛,张凯,吴大畅..皂角刺提取物体外抑菌杀菌作用研究[J].医药导报,2013,32(3):300-302,3.

医药导报

OA北大核心CSTPCD

1004-0781

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