医药导报2013，Vol.32Issue(3)：350-353,4.DOI:10.3870/yydb.2013.03.026
不同提取方法对川芎和香附有效成分溶出度的比较
Comparison of Dissolubility of the Active Ingredients in Ligusticum wallichii and Rhizoma cyperi with Different Extraction Approaches
摘要
Abstract
Objective To compare different extractioin methods for the dissolution of the ligustilide and ferulic acid in Ligusticum wallichii and a-cyperone in Rhizoma cyperi. Methods An HPLC method was established for the determination of ligustilide, ferulic acid and a-cyperone. The content of these index components were extracted via three methods, including alcohol followed by ether, alcohol percolation, and water boiling. Results The total active constituents from the two Chinese medicines had the highest yield from petroleum ether extraction followed by 75% ethanol. Conclusion The combination of division and remerging extraction approach improves the dissolution and extraction rate of active ingredients as well as reduces the loss of unstable components.关键词
川芎/香附/藁本内酯/阿魏酸/α-香附酮Key words
Ligusticum wallichii/Rhizoma cyperi/Ligustilide/Ferulic acid/α-cyperone分类
医药卫生引用本文复制引用
张昕莹,郭淑云,张文娟,王庆伟,徐媛,张婷婷..不同提取方法对川芎和香附有效成分溶出度的比较[J].医药导报,2013,32(3):350-353,4.基金项目
国家自然科学基金资助项目(81102836) （81102836）
