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低取代度两亲性β-环糊精及其水相中纳米球的制备

郭文彦 赵明刚 郝爱友

应用化学2013,Vol.30Issue(3):260-264,5.
应用化学2013,Vol.30Issue(3):260-264,5.DOI:10.3724/SP.J.1095.2013.20164

低取代度两亲性β-环糊精及其水相中纳米球的制备

Synthesis of Amphiphilic β-Cyclodextrins and Their Nanospheres in Water

郭文彦 1赵明刚 1郝爱友1

作者信息

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摘要

Abstract

Four amphiphilic bifunctionalized β-cyclodextrin derivatives with low degree of substitution (DS) were conveniently synthesized via the reaction of 2-O-(2-hydroxypropyl)-β-eyclodextrin with Lauryl glycidol ether, tetradecyl glycidol ether, hexadecyl glycidol ether and octadecyl glycidol ether in pyridine, respectively. The four amphiphilic β-CD derivatives( DS 1. 87, 1. 95 , 2. 14 and 1. 80, respectively) could self-assemble in water to form stable nanospheres with improved dispersion degree and uniformity up to 2 ~ 3 weeks.

关键词

两亲性/O-(羟丙基)-β-环糊精/缩水甘油醚/纳米球

Key words

amphiphilic, O- (hydroxypropyl) -β-cyclodextrin, glycidol ether, nanospheres

分类

化学化工

引用本文复制引用

郭文彦,赵明刚,郝爱友..低取代度两亲性β-环糊精及其水相中纳米球的制备[J].应用化学,2013,30(3):260-264,5.

基金项目

教育部高等学校博士学科点专项科研基金资助(20091404110001) (20091404110001)

应用化学

OA北大核心CSCDCSTPCD

1000-0518

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