中国当代儿科杂志2013，Vol.15Issue(3)：171-174,4.DOI:10.7499/j.issn.1008-8830.2013.03.002
哮喘和咳嗽变异性哮喘儿童肺常规通气功能的比较
Comparative analysis of conventional pulmonary function test results in children with asthma or cough variant asthma
摘要
Abstract
Objective To compare the conventional pulmonary function test results of children with asthma or cough variant asthma (CVA). Methods A total of 140 children, who were diagnosed with asthma or CVA from May 2010 to May 2011, were divided into acute asthma attack (n =50), asthma remission (n =50) and CVA groups (n =40) ; 30 healthy children were included as a control group. The forced vital capacity ( FVC) , forced expiratory volume in one second ( FEV1) , peak expiratory flow ( PEF) , forced expiratory flow after 25% of vital capacity has been expelled ( FEF25 ) , forced expiratory flow after 50% of vital capacity has been expelled (FEF50) , forced expiratory flow after 75% of vital capacity has been expelled ( FEF75 ) and maximal midexpiratory flow ( MMEF75/25 ) were measured. Results The mean percent predicted values of all the above indices were lower than 80% in the acute asthma attack group, with FEF50, FEF75 and MMEF75/25 declining markedly; the mean percent predicted values of FEF75 and MMEF75/25 were lower than 80% in the CVA group. All the pulmonary function indices in the acute asthma attack group were lower than those in the control group. The mean percent predicted values of FVC, FEV1, FEF25 and MMEF75/25 in the asthma remission and CVA groups were lower than in the control group. All the pulmonary function indices in the acute asthma attack group were lower than in the asthma remission and CVA groups, but there were no significant differences between the asthma remission and CVA groups. Conclusions There is small and large airway dysfunction, particularly small airway dysfunction, in children with acute asthma attack. Children with CVA present mainly with mild small airway dysfunction, as do those with asthma in remission.关键词
肺功能/哮喘/咳嗽变异性哮喘/儿童Key words
Pulmonary function/Asthma/Cough variant asthma/Child引用本文复制引用
袁洁,安淑华,高文杰,杜雯瑾,孙军峰,张曼,姚聪卓..哮喘和咳嗽变异性哮喘儿童肺常规通气功能的比较[J].中国当代儿科杂志,2013,15(3):171-174,4.基金项目
河北省医学适用技术跟踪项目(编号:GL200841). （编号:GL200841）
