中国动脉硬化杂志2013，Vol.21Issue(3)：271-274,4.
血液循环和植物来源miRNA的研究进展
The Advance in Research on Circulating and Plant-Drived miRNA
摘要
Abstract
MiRNA are non-coding RNAs with 19-25 nucleotides in length, which play an important role in regulation of gene transcription and translation and greatly contribute to the development of tumor and cardiocerebral vascular diseases. Recently studies show that miRNAs stably exist in the peripheral blood. Changes of miRNA levels in the circulation are closely related to the occurrence, development and prognosis of multiple diseases. Therefore miRNAs may be a novel class of biomarkers for diseases. Plant-derived miRNAs can also stably exist in the blood and participate in the regulation of many target proteins of animals. It is of great significance to assess the efficacy of traditional Chinese medicine and to clarify the underlying mechanisms through examining the changes of plant-derived miRNA levels in the blood.关键词
循环miRNA/植物来源miRNA/疾病标记物/中药机制Key words
Circulating miRNA/Plant-derived miRNA/Disease Biomarker/Mechanisms of Chinese Medicine分类
医药卫生引用本文复制引用
杨中保..血液循环和植物来源miRNA的研究进展[J].中国动脉硬化杂志,2013,21(3):271-274,4.基金项目
国家自然科学基金资助项目(30971194) （30971194）
