中国临床医学2013,Vol.20Issue(1):27-28,2.
血浆N氨基末端脑钠肽前体水平及QRS积分对急性ST段抬高型心肌梗死患者预后的预测价值
Prognostic Value of Plasma N-Terminal Pro-Brain Natriuretic Peptide Level and QRS Scoring in ST-Segment Elevation Myocardial Infarction
摘要
Abstract
Objective:To investigate the prognostic values of plasma N-terminal pro-brain natriuretic peptide(NT-proBNP) and QRS scoring in patients with ST-segment elevation myocardial infarction(STEMI) undergoing emergent percutaneous coronary intervention. Methods: A total of 98 patients with STEMI from July 2009 to July 2011 have been involved in this study. Plasma NT-proBNP levels were detected with enzyme-linked immunosorbent assay and QRS scoring was evaluated a week later after in farction. Cardiovascular events, including postinfarction angina pectoris, recurrent myocardial infarction and cardiovascular death were observed in all patients during the follow-up period of six months. Plasma NT-proBNP level and QRS scoring were compared between the cardiovascular event group and no cardiovascular event group. Results: In 98 patients, 37 patients had cardiovascular events and 61 patients had no cardiovascular events. The level of plasma NT-proBNP [(1040. 8 ± 377. 2) pg/ ml] and QRS scoring (6. 5 ± 0. 5) in cardiovascular event group were higher than those in no cardiovascular event group [(309. 9 ± 134.2) pg/mL.4. 3 ± 0. 4], and the differences were significant(P<0. 01 ,P<0. 05 .respectively). The level of plasma NT-proBNP was positively correlated with QRS scoring(r= 0. 618,P<0. 05). Conclusions: Plasma NT-proBNP and QRS scoring were sensitive indicators in reflecting the occurrence of cardiovascular events within six months after STEMI, and it can predict the recent prognosis of patients with STEMI.关键词
N氨基末端脑钠肽前体/QRS积分/急性ST段抬高型心肌梗死/近期预后Key words
N-terminal pro-brain natriuretic peptide/QRS scoring/ST-segment elevation myocardial infarction/Recent prognosis分类
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芦涤,魏洪杰,朱铭..血浆N氨基末端脑钠肽前体水平及QRS积分对急性ST段抬高型心肌梗死患者预后的预测价值[J].中国临床医学,2013,20(1):27-28,2.