中国实用妇科与产科杂志2013，Vol.29Issue(3)：197-199,3.
荧光原位杂交技术在产前诊断中的应用价值
Application value of fluorescence in situ hybridization for prenatal diagnosis
柳宛璐 1乔福元 1唐红菊 1丁建林 1吴行飞 1石鑫玮 1李宇琪 1唐桂菊 1陈平1
作者信息
摘要
Abstract
Objective To evaluate application value of fluorescence in situ hybridization for prenatal diagnosis. Methods 1148 cases of pregnant women in Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology were taken amniotic fluid for FISH technology on interphase nuclear cell chromosome number detection between November 2009 and August 2012. Results 1148 cases of pregnant were diagnosed with fetal trisomy 21-syndrome in 28 cases; 18-trisomy syndrome in 7 cases; 13-trisomy syndrome in 2 cases; 45, XO (Tuner' s syndrome) in 1 case; 47, XXY and 47, XYY in 1 case respctively; 40 cases of children with chromosomal abnormalities were detected totally. Conclusion FISH is a rapid and accurate method for prenatal diagnosis of chromosome aneuploidies.关键词
荧光原位杂交/羊膜腔穿刺/产前诊断Key words
fluorescence in situ hybridization/ amnion cavity puncture/ prenatal diagnosis分类
医药卫生引用本文复制引用
柳宛璐,乔福元,唐红菊,丁建林,吴行飞,石鑫玮,李宇琪,唐桂菊,陈平..荧光原位杂交技术在产前诊断中的应用价值[J].中国实用妇科与产科杂志,2013,29(3):197-199,3.
