中国实用内科杂志2013,Vol.33Issue(3):217-219,3.
数字连接实验和数字符号实验联合应用诊断轻微肝性脑病价值研究
Significance of number connection test and digit symbol tests for the diagnosis of minimal hepatic encephalopathy
摘要
Abstract
Objective To explore the significance of number connection test (NCT) and digit symbol test (DST) for the diagnosis of minimal hepatic encephalopathy (MHE). Methods A total of 65 patients with hepatitis B-associated cirrhosis were recruited from the department of gastroenterology, the First People's Hospital of Yunnan Province. We also enrolled ninety healthy volunteers with an educational background for > 12 years as normal controls. The NCT-A and DST were employed for assessment. Results The diagnostic yield for the combination of NCT-A and DST was 46% (30/65). Prolonged duration of NCT-A was linked to the increasing severity of Child-Pugh stages (P < 0. 05), which was associated with progressively reduced DST score (P < 0. 05). Conclusion Featured by high feasibility and convenience, the combination of NCT-A and DST is useful to the diagnosis of MHE and may reduce the rates for misdiagnosis and underdiagnosis. In view of high cost-effectiveness, the combination may be particularly suitable for out-patient screening and long-term follow-up investigation following patients' discharge from the hospital.关键词
轻微肝性脑病/数字连接实验/数字符号实验Key words
minimal hepatic encephalopathy/ number connection test/ digit symbol tests分类
医药卫生引用本文复制引用
翟慧勤,范红,寻琳婷,王芸..数字连接实验和数字符号实验联合应用诊断轻微肝性脑病价值研究[J].中国实用内科杂志,2013,33(3):217-219,3.基金项目
国家自然科学基金资助(81260077) (81260077)