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NNK和B[a]P在卷烟烟气复杂基质中的联合遗传毒性

木潆 朱茂祥 潘秀颉 杨陟华 齐绍武

中国烟草学报2013,Vol.19Issue(1):76-80,5.
中国烟草学报2013,Vol.19Issue(1):76-80,5.DOI:10.3969/j.issn.1004-5708.2012.05.015

NNK和B[a]P在卷烟烟气复杂基质中的联合遗传毒性

The Synergic genetic toxicity of NNK and B[a]P in cigarette smoke condensates

木潆 1朱茂祥 1潘秀颉 1杨陟华 1齐绍武1

作者信息

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摘要

Abstract

The Synergic Genetic Toxicity of NNK and B[a]P in cigarette smoke condensates (CSC) was studied with Kentucky reference cigarettes 3R4F. Micronucleus test was carried out and their toxity effects for BEAS-2B cells were determined. Result shows that: 1) B[a]P, NNK and CSC all showed genetic toxicity; 2) there existed antagonism between any two of the three; 3) joint action of the three display some synergism.

关键词

卷烟烟气冷凝物(CSC)/NNK/B[a]P/遗传毒性

Key words

cigarette smoke condensates (CSC)/ NNK/ B[a]P/ genetic toxicity

分类

农业科技

引用本文复制引用

木潆,朱茂祥,潘秀颉,杨陟华,齐绍武..NNK和B[a]P在卷烟烟气复杂基质中的联合遗传毒性[J].中国烟草学报,2013,19(1):76-80,5.

基金项目

中国烟草总公司科技项目(110200801022) (110200801022)

中国烟草学报

OA北大核心CSCDCSTPCD

1004-5708

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