摘要
Abstract
OBJECTIVE: To evaluate the utilization of quinolones in the hospitals from Nanjing areas. METHEDS: By a retrospective study, the consumption sum, DDDs and DDC of quinolones in 35 hospitals from Nanjing area during 2009 - 2011 were analyzed statistically in respect of consumption sum, DDDs and DDC, etc. RESULTS: During 3-year period, the consumption sum and DDDs of quinolones in 35 hospitals reduced year by year. The consumption sum were 83 172 965.10 yuan, 76 225 513.46 yuan,62 876 382.09 yuan, respectively, with annual growth rate of -13.05%. DDDs were 2 910 542.73,2 478 391.70 and 2 512 051.15, respectively, with annual growth rate of -7.10%. DDDs of levofloxacin had ranked first during 3-year period. The DDDs were 1 102 525.40, 992 019.80 and 1 290 872.60 respectively, accounting for 42.85% of the total DDDs of quinolones. The consumption sum and DDDs of Moxifloxacin injection increased year by year; the consumption sum were 11 781 874.56 yuan, 13 120 229.39 yuan and 15 527 001.24 yuan respectively; DDDs were 41 092.00, 45 903.00 and 56 016.00, respectively; DDC were 286.72 yuan, 285.83 yuan and 277.19 yuan, respectively. Except for Pazufloxacin injection, the consumption sum and DDDs of other varieties exhibited a downward trend. In 2010, 3 kinds of quinolones(pipemidic acid, pefloxacin, tosuflox-acin)were eliminated and a new variety of quinolones(antofloxacin) was introduced. CONCLUSIONS: The application of quinolones in 35 hospitals from Nanjing area is decreasing year by year. To delay the generation of bacterial resistance, the strict control of the application of quinolones is recommended to ensure safe, effective and economical use of drugs in the clinic.关键词
喹诺酮类药/利用分析/用药频度/日均费用/序号比值Key words
Quinolones/ Utilization analysis/DDDs/ DDC/ Serial number ratio分类
医药卫生
