中国药房2013，Vol.24Issue(14)：1308-1310,3.DOI:10.6039/j.issn.1001-0408.2013.14.24
我院609例药源性皮疹病例分析
Analysis of 609 Cases of Drug-induced Skin Rash in Our Hospital
摘要
Abstract
OBJECTIVE: To investigate the occurrence of drug-induced skin rash (drug rash). METHODS: By descriptive study, 609 cases of drug rash in our hospital from Apr. 1999 to Mar. 2012 were analyzed retrospectively. RESULTS: Among 609 cases of drug rash, male cases was less than female cases with the ratio of 1:1.31; there were 514 single medication cases and 95 combined medication cases; there were 159 mild cases, 443 moderate cases and 7 severe cases; 501 cases were symptomatically treated, 108 cases were not given special treatment; 609 patients were all fully recovered; in the cause-effect relationship assessment, there were 3 certain cases, 458 probable cases and 148 possible cases; 98 drugs were suspected of drug-induced skin rash in 609 cases; the anti-infective drug rash accounted for 65.35% ; drug rash induced by TCM preparation and central nervous system drugs accounted for 15.44% and 8.37% respectively; exanthematic eruption accounted for 47.95% , followed by urticaria eruption and erythema multiforme, accounting for 30.71% and 15.44% respectively. CONCLUSIONS:Great improtance should be attached to the drug rash. In order to reduce the occurrence of the drug rash, drugs should be used in a rational way, especially for the patients with allergic history.关键词
药源性皮疹/病例分析/药品不良反应Key words
Drug-induced skin rash/ Case analysis/ Adverse drug reactions分类
医药卫生引用本文复制引用
杨君,黄仲义..我院609例药源性皮疹病例分析[J].中国药房,2013,24(14):1308-1310,3.
