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类风湿关节炎伴周围神经病7例

毕丹艳 毕丹青 李芹 张虹 晋松 范宏涛 王静 何彦春

中华临床免疫和变态反应杂志2013,Vol.7Issue(1):63-66,4.
中华临床免疫和变态反应杂志2013,Vol.7Issue(1):63-66,4.

类风湿关节炎伴周围神经病7例

Peripheral Neuropathy in Seven Patients with Rheumatoid Arthritis

毕丹艳 1毕丹青 1李芹 1张虹 1晋松 1范宏涛 1王静 1何彦春1

作者信息

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摘要

Abstract

Objective To investigate the clinical features and prognosis of rheumatoid arthritis ( RA) associated with multiple peripheral neuropathy and to raise awareness of the disease. Methods A retrospective analysis of clinical data from seven cases of rheumatoid arthritis with peripheral neuropathy. Results seven patients all showed various degrees of limb muscle strength decline and significantly increased erythrocyte sedimentation rate , C reactive protein , rheumatoid factor. Electromyography revealed neurogenic injury in all patients. Patients were given glucocorticoid and immunosuppressants treatment, and 2 cases were treated with etanercept. The inflammatory markers were improved significantly, symptoms of numbness of the limbs, distal hypoesthesia were improved as well. However , muscle atrophy , wristdrop and footdrop didn ' t show Significant changes. Conclusions The early symptom of multiple peripheral neuropathy associated with RA is not obvious, and is easily overlooked, even leading to irreversible consequence. Early diagnosis and treatment is important for good prognosis.

关键词

类风湿关节炎/周围神经病/肌电图

Key words

rheumatoid arthritis/ peripheral neuropathy/ electromygraphy

分类

医药卫生

引用本文复制引用

毕丹艳,毕丹青,李芹,张虹,晋松,范宏涛,王静,何彦春..类风湿关节炎伴周围神经病7例[J].中华临床免疫和变态反应杂志,2013,7(1):63-66,4.

中华临床免疫和变态反应杂志

OACSTPCD

1673-8705

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