中山大学学报(自然科学版)2013,Vol.52Issue(2):97-100,4.
复方血栓通胶囊基于血液循环和凝血过程相关靶点的网络药理学研究
Network Pharmacology Study of Compound Xueshuantong Capsule Based on the Targets Related to Blood Circulation and Hemostasis
摘要
Abstract
Network pharmacology based on the computational molecular docking was used to study interaction of chemical composition of Compound Xueshuantong Capsule to the targets related to blood circulation and hemostasis. A compound-target interaction network diagram was generated. The results showed that the chemical compounds of Compound Xueshuantong Capsule interacts with the multiple targets, such as ACE and PDE, revealing the multitargeted regulatory mechanism of Compound Xueshuantong Capsules in the treatment of retinal vein occlusion on molecular level.关键词
复方血栓通胶囊/网络药理学/分子对接Key words
Compound Xueshuantong Capsule/ network pharmacology/ molecular docking分类
医药卫生引用本文复制引用
刘忠政,梁洁萍,聂怡初,刘宏,谢称石,程国华,苏薇薇..复方血栓通胶囊基于血液循环和凝血过程相关靶点的网络药理学研究[J].中山大学学报(自然科学版),2013,52(2):97-100,4.基金项目
国家"重大新药创制"科技重大专项资助项目(2011ZX09201-201-22) (2011ZX09201-201-22)
国家科技支撑计划课题资助项目(2012 BAT29B09) (2012 BAT29B09)
东莞医疗卫生单位科技计划资助项目(2012105102004) (2012105102004)