国际医药卫生导报2013，Vol.19Issue(5)：661-663,3.DOI:10.3760/cma.j.issn.1007-1245.2013.05.025
盐酸氨溴索与肺表面活性物质治疗新生儿呼吸窘迫综合征128例临床疗效分析
Ambroxol hydrochloride combined with pulmonary surfactant for neonatal respiratory distress syndrome in 128 pediatric patients
摘要
Abstract
Objective To explore the clinical efficacy of ambroxol hydrochloride in the treatment of neonatal respiratory distress syndrome (NRDS).Methods 128 pediatric patients with NRDS who had been hospitalized during the period of May 2007 to September 2011 were randomly divided into two groups.The control group (64 patients) received therapy with pulmonary surfactant,while the study group (64 patients) received additional ambroxol hydrochloride.The efficacy was compared between the two groups.Resuts The dose of pulmonary surfactant uses was (198.5 ± 49.3)mg,duration of mechanical ventilation was (78.4 ± 18.4)h,length of hospital stay was (18.5 ± 5.6)d,rate of complications was 31.3％,and mortality rate was 10.9％ in the control group; while the dose of pulmonary surfactant uses was (134.1 ± 33.6)mg,duration of mechanical ventilation was (56.1 ± 11.9)h,length of hospital stay was (11.2 ± 3.8)d,rate of complications was 12.5％,and mortality rate was 1.6％ in the study group,with significant differences (P＜0.05).Conclusions Ambroxol hydrochloride combined with pulmonary surfactant in the treatment of neonatal respiratory distress syndrome is satisfactory and it is worth popularizing clinically.关键词
盐酸氨溴索/肺表面活性物质/新生儿呼吸窘迫综合征Key words
Ambroxol hydrochloride/ Pulmonary surfactant/ Neonatal respiratory distress syndrome引用本文复制引用
江霞辉,陆俏群,赵若雯..盐酸氨溴索与肺表面活性物质治疗新生儿呼吸窘迫综合征128例临床疗效分析[J].国际医药卫生导报,2013,19(5):661-663,3.
