实用临床医药杂志2013,Vol.17Issue(3):22-24,31,4.DOI:10.7619/jcmp.201303007
常规二维放疗和三维适形调强放疗对食管癌的疗效分析
An analysis of the therapeutic effects of three-dimensional intensity modulated radiation therapy and two-dimensional conventional radiotherapy on esophageal carcinoma
摘要
Abstract
Objective To explore the therapeutic effects and safety of three - dimensional intensity modulated radiation therapy (3D-IMRT) and two - dimensional general radiotherapy on esopha-geal carcinoma. Methods Eighty -six esophageal cancer patients were divided into two groups; 3D-IMRT group and two - dimensional conventional radiotherapy group ( general radiotherapy group). The differences between short - term and long - term therapeutic effects as well as toxic and side effects in two groups were compared. Results The total effectiveness rate of 3D-IMRT group significantly was higher than that of general radiotherapy group. The incidence of radiation pneumonitis in general radiotherapy group was significantly higher than that in 3D-IMRT group. The 1,2,3,5- year local control rates and 1,2,3 -year survival rates in 3D-IMRT group were significantly hiher than those in general radiotherapy group. Conclusion Compared with two -dimensional conventional radiotherapy, 3D-IMRT can markedly enhance the short - term therapeutic effects of esophageal carcinoma, improve its local control rate and survival rate, and effectively alleviate the damage of surrounding tissues induced by radiotherapy.关键词
适形调强放疗/常规放疗/食管癌Key words
intensity modulated radiation therapy/ conventional radiotherapy/ esophageal carcinoma分类
医药卫生引用本文复制引用
叶奕菁,张晶晶,陆小军,徐桂琼,欧阳玉秀,刘玉猛..常规二维放疗和三维适形调强放疗对食管癌的疗效分析[J].实用临床医药杂志,2013,17(3):22-24,31,4.基金项目
中国高校医学期刊临床专项资金(11320005) (11320005)