实用临床医药杂志2013，Vol.17Issue(3)：28-31,4.DOI:10.7619/jcmp.201303009
64层螺旋CT联合超敏C反应蛋白、D-二聚体、同型半胱氨酸检测急性冠脉综合征患者冠状动脉斑块稳定性的临床价值
Clinical value of 64-multislice spiral computed tomography combined with high-sensitivity C-reactive protein, D-dimer and homocysteine for detecting the stability of coronary arteryplaques of patients with acute coronary syndrome
摘要
Abstract
Objective To investigate the clinical value of 64-multislice spiral computed tomography (64-MSCT) combined with high-sensitivity C-reactive protein (hsCRP), D-dimer and homocysteine (Hcy) for detecting the stability of coronary artery plaques of patients with acute coronary syndrome (ACS). Methods Ninety-six patients conducted with coronary angiography and CT tomography were divided into ACS group (n = 31), stable angina pectoris (SAP) group (n = 35) and control group (n=30). According to the results of coronary artery plaques detected by MSCT, both ACS and SAP groups were further divided into vulnerable plaque group, mixed plaque group and stable plaque group, 22 cases in each group. The levels of serum hsCRP and Hcy, plasma as well as D-dimer were detected, and 64-MSCT was used to judge the nature of coronary atherosclerotic plaques. Results The distribution of vulnerable and mixed plaques in ACS group was dramatically higher than that in SAP group, while that of stable plaques lower than in SAP group. The levels of hsCRP, D-dimer and Hcy in SAP and ACS groups were conspicuously higher than those in control group, and there was significant difference between SAP and ACS groups. The levels of hsCRP, D-dimer and Hcy in every plaque group were all obviously higher than those in the control group, and those in vulnerable and mixed plaque groups were also distinctly higher than those in stable plaque group. The levels of hsCRP and D-dimer in vulnerable plaque group were clearly higher than those in mixed plaque group. Conclusion The detection of 64-MSCT combined with hsCRP, D-dimer and Hcy can be considered as a predictive indicator of unstable coronary artery plaques.关键词
64层螺旋CT/超敏C反应蛋白/D-二聚体/同型半胱氨酸/急性冠脉综合征Key words
64-multislice spiral computed tomography/ high-sensitivity C-reactive protein/ D-dimer/ homocysteine/ acute coronary syndrome分类
医药卫生引用本文复制引用
朱莉,徐彧..64层螺旋CT联合超敏C反应蛋白、D-二聚体、同型半胱氨酸检测急性冠脉综合征患者冠状动脉斑块稳定性的临床价值[J].实用临床医药杂志,2013,17(3):28-31,4.基金项目
中国高校医学期刊临床专项资金(11320008) （11320008）
