实用临床医药杂志2013，Vol.17Issue(3)：84-87,4.DOI:10.7619/jcmp.201303027
舒芬太尼经鼻给药复合帕瑞昔布钠用于鼻内窥镜术后镇痛
Efficiency and safety of multimodal analgesia use in nasal endoscope operation with the compound of sufentanil with parecoxib sodium through nose
摘要
Abstract
Objective To observe the efficiency and safety of multimodal analgesia use in nasal endoscope operation with the compound of sufentanil with parecoxib sodium through nose. Meathods Sixty nasal endoscope operation patients were divided into three groups randomly. Group A was S1 group, 2 μg sufentanil was administered through nose after operation, and 40 mg parecoxib sodium was injected. Group B was S2 group, 15 μg sufentanil was administered through nose after operation, and 40 mg parecoxib sodium was injected. Group C was administered physiological saline through nose after operation, and was injected with 40 mg parecoxib sodium. Systolic pressure(SBP), diastolic pressure(DBP), mean arterial pressure (MAP) and heart rate (HR) were recorded respectively immediately at operation (T0) ,10 minutes before extubation(T1), extubation (T2) and 10 minutes after extubation(T3). And visual pain analog scale (VAS) was recorded respectively 10 minutes after anesthesia for awake after extubation, 4 hours after operation, 12 hours after operation and 24 hours after operation. Adverse reaction 24 hours after operation was recorded as well. Results SBP, DBP, MAP and HR of group S1 and group S2 at the moment of T2 and T3 were obviously lower than group C (P<0.05). Visual pain analog scale of group S1 at each moment was obviously better than group C (P < 0. 05). Conclusion Twenty - fiveμg sufentanil through nose after operation combined with injection of 40 mg parecoxib sodium can relieve pain after operation noticeably and safely.关键词
舒芬太尼/帕瑞昔布钠/鼻内窥镜/多模式镇痛Key words
sufentanil/ parecoxib sodium/ nasal endoscope/ multimodal analgesia分类
医药卫生引用本文复制引用
施震,陈敏,王庆利,陶军..舒芬太尼经鼻给药复合帕瑞昔布钠用于鼻内窥镜术后镇痛[J].实用临床医药杂志,2013,17(3):84-87,4.
