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真菌性血流感染菌种分布及耐药性分析

梁珺 张洲 徐元宏

临床输血与检验2013,Vol.15Issue(2):101-104,4.
临床输血与检验2013,Vol.15Issue(2):101-104,4.DOI:10.3969/j.issn.1671-2587.2013.02.002

真菌性血流感染菌种分布及耐药性分析

Fungal Species Distribution and Drug Resistance of Bloodstream Infection

梁珺 1张洲 1徐元宏1

作者信息

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摘要

Abstract

Objective To survey the status of fungal infection of blood culture specimen in hospital, and provide the basis for clinical diagnosis and treatment. Methods The retrospective analysis was used to test the results of blood cultures in our hospital in 2011. and the distribution and antibiotic resistance for the fungal infections were analyzed. Results Hospital submission of blood culture samples were 5 093 in 2011,473 pathogens were detected, including the detection of 39 fungi. The fungal isolation rate was 0. 77%, accounting for 7. 8% of the pathogens which were detected. The largest number was Candida albicans, followed by Candida parapsilosis and Candida tropicalis. The number of neonatology ranked top in the distribution of the main sections, followed by the department of Hematology and ICU. The sensitivity of 39 fungi to the five antimicrobia agents: 5-fluorocytosine (100. 00%), amphotericin B (97. 40%),voriconazole (94. 90%), flu-conazole (92.30%), itraconazole (89.70%). Conclusion Candida albicans is the majority of blood infected fungus, which mainly distributed in neonatology. And 5-fluorocytosine resistant strains have not been found, resistance to the antifungal agents have increased.

关键词

血流感染/真菌/耐药性

Key words

Bloodstream infection/Fungi/Resistance

分类

医药卫生

引用本文复制引用

梁珺,张洲,徐元宏..真菌性血流感染菌种分布及耐药性分析[J].临床输血与检验,2013,15(2):101-104,4.

基金项目

本课题受安徽省卫生厅临床医学课题(No.2010C052)、安徽省教育厅自然科学课题(No.KJ2011A181)资助 (No.2010C052)

临床输血与检验

OACSTPCD

1671-2587

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