临床输血与检验2013，Vol.15Issue(2)：135-138,4.DOI:10.3969/j.issn.1671-2587.2013.02.011
B(A)血型的鉴定及临床输注探讨
Identification and Clinical Infusion of B (A) Blood Group
郑望春 1骆宏 1叶有玩 1沈磁石 1黄华霖1
作者信息
摘要
Abstract
Objective To explore the identification and clinical infusion of B(A) blood group. Methods B(A) blood groups and B(A) alleles of the samples were checked out by serology and direct sequencing and cloning sequencing of ABO gene exon 6 and 7. Retrospective experiment records were collected to analyze the clinical infusion. Results The serological results of the blood sample was shown as B(A). Result of the sequencing analysis showed the sample harbored an O01 allele.and had the nt640 A/G mutation in B gene,which was previously defined as B(A) 04. B(A) blood of donor was infused to type B receptor,whose Hb rising conformed to the expected value, no adverse reaction of blood transfusion occurred. Conclusion The sample is identified as B(A) phenotype in serological tests, whose genotype is rare B(A)04 / O01. Under the consistency of cross matching.it is safe and effective for the blood of B (A) blood donor infused to type B receptor.
关键词
血型/ABO基因/核苷酸序列分析/输血Key words
Blood group/ABO genotype/ Nucleic acid equence analysis/Transfusion分类
医药卫生引用本文复制引用
郑望春,骆宏,叶有玩,沈磁石,黄华霖..B(A)血型的鉴定及临床输注探讨[J].临床输血与检验,2013,15(2):135-138,4.
