山东医药2013，Vol.53Issue(15)：38-40,3.DOI:10.3969/j.issn.1002-266X.2013.15.014
低流量单肺通气对肺癌手术患者呼吸功能的影响
Effects of low flow anesthesia on respiratory function during one lung ventilation in patients with lung cancer surgery
摘要
Abstract
Objective To investigate the effects of low flow anesthesia on respiratory function during one lung ventilation in patients with lung cancer surgery. Methods A total of 40 ASA I or II grade patients, scheduled for lung cancer surgery under one lung ventilation ( OLV) were randomly divided into two groups with 20 each: normal flow anesthesia group( Group A) and low flow anesthesia group( Group B). Before OLV, two groups received high oxygen flow of 4 L/min and inhaled 1 % enflurane for ten minutes, then the oxygen flow was decreased to 3 L/min in group A and 1 L/min in group B, and two groups received high flow fresh gas of 4 L/min per 60 minutes for 5 minutes during OLV. The inhalation of enflurane was stopped at 30 min before operation cease and then the oxygen flow was recovered to 4 L/min until operation cease. Peak airway pressure( Ppeak) , mean airway pressure( Pmean) , airway resistance( Raw) , lung compliance( Cdyn) , arterial oxygen pressure( PaO2) , carbon dioxide pressure( PaCO2 ) were recorded before OLV(T0) and at 10 min(T1 ) , 30 min(T2) , 60 min(T3) min after OLV, 30 min (T4) after two lung ventilation. Results Ppeak, Pmean, Raw were increased (all P <0. 01) and Cdyn, PaO2 were decreased from T1 to T3 when compared with T0 in two groups (all P <0. 01) , there was no significant difference in other parameters from T0 to T4 between the two groups. Conclusion Low flow anesthesia has little effect on respiratory function in patients with lung cancer surgery. Low flow anesthesia can be safely used for one-lung ventilation.关键词
麻醉/低流量麻醉/单肺通气/呼吸功能Key words
anesthesia/low flow anesthesia/one lung ventilation/respiratory function分类
医药卫生引用本文复制引用
胡彦艳,秦丹丹,叶凤青,黄中华,李静,黄爱兰..低流量单肺通气对肺癌手术患者呼吸功能的影响[J].山东医药,2013,53(15):38-40,3.基金项目
广西壮族自治区自然科学基金资助项目(0339020). （0339020）
