陕西医学杂志2013，Vol.42Issue(5)：546-548,3.
帕瑞昔布治疗神经外科患者全麻术后急性疼痛60例
Clinical efficacy of Parecoxib for acute postoperative pain after propofol and remifentanil-induced anesthesia in neurosurgery patients
赵敏 1张霞婧 1高淅 1朱萧玲 1王强 1陈绍洋1
作者信息
摘要
Abstract
Objective : To observe the effect of parecoxib on acute postoperative pain after propofol and remifentanil-induced anesthesia in neurosurgery patients . Methods :60 patients undergoing neurosurgery were randomized to two groups . After intubation , 5ml normal saline (group C)and 40mg Parecoxib (group P)were intravenously infused , postoperative pain was accessed at 30min、2h、6h、12h、24h h after surgery by VAS scores . Incidences of the adverse reactions , such as restlessness in stage of analepsia , bucking , were observed . Pre-/post-surgical hepatic and renal functions were tested . Results : 30min,2h,6h after surgery , VAS scores in group P were apparentely lower than those of group C(P<0 .05), whereas there was no significant differences between two groups at 12,24h (P＞0 .05) . Pre-/post-surgical hepatic and renal functions showed no significant difference (P＞0 .05) .Conclusion : Parecoxib relieves acute postoperative pain after propofol and remifentanil-induced anesthesia in neurosurgery patients , decreases the incidences of restlessness in stage of analepsia , bucking and has no harmful effects on hepatic and renal functions .关键词
疼痛,手术后/药物疗法/消炎药,非甾类/治疗应用/麻醉,全身/神经外科手术Key words
Pain postoperative/drug therapy / Anti-inflammatory agents ,non-sterioidal/therapeutic use Anesthesia,general / Neuosurgical procedures
分类
医药卫生引用本文复制引用
赵敏,张霞婧,高淅,朱萧玲,王强,陈绍洋..帕瑞昔布治疗神经外科患者全麻术后急性疼痛60例[J].陕西医学杂志,2013,42(5):546-548,3.
