天然产物研究与开发2013，Vol.25Issue(3)：302-306,328,6.
产α-葡萄糖苷酶抑制剂乳酸菌的筛选及发酵条件优化
Screening of Lactic Acid Bacteria Strains Capable of Biosynthesis α-Glucosidase Inhibitors
摘要
Abstract
The inhibitory effect of fermented soybean milks by a variety of lactic acid bacteria strains on maltase (EC 3. 2. 1.20) was assayed in vitro. Among the tested strains,Lactobacillus plantarum ST-Ⅲ demonstrated the highest capability to synthesize α-glucosidase inhibitors in the soybean milk at 37 ℃. The fermentation conditions for Lb. Plantarum ST-Ⅲ to biosynthesize α-glucosidase inhibitors in soybean milk were investigated via single factor experiments and the optimized condition was found to be a combination of inoculation ratio of 2% (v/v) ,solid content of soybean milk of 5% (w/v) and fermentation temperature of 37 ℃ ,respectively. Under the optimized conditions,the maltase inhibitory rate of soybean milk fermented by Lb. Plantarum ST-Ⅲ reached 80%.关键词
植物乳杆菌ST-Ⅲ/大豆豆浆/α-葡萄糖苷酶抑制剂/麦芽糖酶Key words
Lactobacillus plantarum ST-Ⅲ/soybean milk/α-glucosidase inhibitor/maltase分类
生物科学引用本文复制引用
韩瑨,季红,周方方,吴正钧..产α-葡萄糖苷酶抑制剂乳酸菌的筛选及发酵条件优化[J].天然产物研究与开发,2013,25(3):302-306,328,6.基金项目
科技部"十二五"科技支撑计划(2012BAD28B08) （2012BAD28B08）
科技部973计划课题(2012CB723706) （2012CB723706）
