质谱学报2013，Vol.34Issue(2)：65-74,10.DOI:10.7538/zpxb.2013.34.02.0065
质谱电喷雾电离源研究新进展
Advances of Electrospray Ionization Source for Mass Spectrometry
摘要
Abstract
The electrospray ionization(ESI) source has been widely used for the identication and quantification of macromolecules especially biomacromolecules since John Fenn developed the soft ion source in 1984. ESI suffers from low sampling efficiency consisting of ionization efficiency and transmission efficiency, which directly limits the detection sensitivity of a mass spectrometer. So scientists working in this field have paid great attention to improve sampling efficiency. In this review, the theory of ESI source is introduced in detail, and the recent improvement of electrospray ionization source is reviewed.关键词
电喷雾离子源/离子化效率/取样效率Key words
electrospray ionization source/ ionization efficiency/ sampling efficiency分类
化学化工引用本文复制引用
李佳斌,郝斐然,田芳,张养军..质谱电喷雾电离源研究新进展[J].质谱学报,2013,34(2):65-74,10.基金项目
国家自然科学基金项目(20735005、20905077) （20735005、20905077）
国家重大科学计划项目(2012CB910603、2010CB912704) （2012CB910603、2010CB912704）
国家重大科学仪器设备开发专项(2011YQ030139、2011YQ06008408和2011YQ09000504)资助 （2011YQ030139、2011YQ06008408和2011YQ09000504）
