质谱学报2013，Vol.34Issue(2)：110-114,5.DOI:10.7538/zpxb.2013.34.02.0110
气相色谱-串联四极杆质谱法测定主流烟气中的苯并[a]芘
Determination of Benzo(a)pyrene in Mainstream Cigarette Smoke by GC-QqQ-MS/MS
尉朝 1孙海峰 1陈嘉彬 1谢涛 1王芳1
作者信息
摘要
Abstract
A GC-QqQ-MS/MS method for the analysis of benzo(a)pyrene in mainstream cigarette smoke was demonstrated. The total particulate matter (TPM) of 20 cigarettes in mainstream smoke were trapped by Cambridge filter pad under standard smoking condition and extracted by cyclohexane with internal standard (ISTD). The solution was analyzed by GC-QqQ-MS/MS with positive ESI under multiple reaction monitoring (MRM) mode after being cleaned upon solid phase extraction and determined by ISTD method under the optimized conditions. The calibration curves show good linearity for benzo(a)pyrene in the concentration ranges of 0. 4-20 /μg/cig and the correlation coefficient is 0. 999 92. The LOQ is 0. 073 μg/L, the largest repeatability coefficient of variation is 3. 71%, and the standard recovery rates are 95. 7%-103. 9%. Ease of operation, shorter procedure and little solvent make it suitable for benzo(a)pyrene determination, especially for low tar cigarettes.关键词
三重串联四极杆/气质联用/苯并[a]芘/多反应监测/主流烟气Key words
triple quadrupole(QqQ)/ GC-MS/MS/ benzo(a) pyrene/ MRM/ mainstream cigarette smoke分类
化学化工引用本文复制引用
尉朝,孙海峰,陈嘉彬,谢涛,王芳..气相色谱-串联四极杆质谱法测定主流烟气中的苯并[a]芘[J].质谱学报,2013,34(2):110-114,5.
