基础医学与临床2013，Vol.33Issue(4)：504-507,4.
胰高血糖素样肽-1及类似物对心血管系统作用的研究进展
Research progress on the effect of glucagon-like peptide-1 and analogues in the cardiovascular system
李礼 1马康华 1罗素新1
作者信息
- 1. 重庆医科大学附属第一医院心血管内科,重庆400016
- 折叠
摘要
Abstract
Glucagon-like peptide-1 (GLP-1) because of its hypoglycemic effect, brings a new occasion to the treatment of type 2 diabetes in clinical practice. Cardiovascular disease is a common complication of diabetes, the study found that GLP-1 and analogs can improve endothelial function, inhibit inflammation, reduce infarct size and ischemia/reperfusion injury, inhibition of cardiomyocyte apoptosis and improve myocardial energy metabolism. These roles can reduce the risk of cardiovascular disease and provide new ways and means for clinical treatment of cardiovascular diseases.关键词
胰高血糖素样肽-1/类似物/心血管系统/2型糖尿病Key words
glucagon-like peptide-1/ analogues/ cardiovascular system/ type 2 diabetes mellitus分类
医药卫生引用本文复制引用
李礼,马康华,罗素新..胰高血糖素样肽-1及类似物对心血管系统作用的研究进展[J].基础医学与临床,2013,33(4):504-507,4.
