临床眼科杂志2013，Vol.21Issue(2)：146-149,4.DOI:10.3969/j.issn.1006-8422.2013.02.019
左旋多巴联合综合疗法治疗青少年屈光不正性弱视的疗效观察
Efficacy of levodopa combined comprehensive treatment on the youth of ametropic amblyopia
摘要
Abstract
Objective Amblyopia is common disease in children. The treatment on the youth of amblyopia was also a focus and difficulty of past study. Present study is to investigate the efficacy of levodopa combined comprehensive treatment on the youth of ametropic amblyopia by comparing with isolated comprehensive therapy. Methods Totally 137 eyes of 76 cases of ametropic amblyopic children aged over 12 were divided into two groups randomly. The control group had comprehensive treatment. Besides the comprehensive treatment, the experimental group had been treated by levodopa for 6 months. After 6 months of treatment, visual acuity, pattern-visual evoked potential( P-VEP) ,contrast sensitivity, fusion, near stereoacuity and distance stereoacuity were tested and analyzed. Results The effective rates of amblyopia in experimental group and control group were 81.82%、56. 34% respectively. There was a significant difference in the effect rate between experimental group and control group ( P < 0.05 ). Also the latency and ampitude of P100 of P-VEP of amblyopia were a significant difference in the effect rate between experimental group and control group ( P <0.05). The experimental group was better than the control group on the improvement of contrast sensitivity, fusion , near and distance stereoacuity ( P < 0.05). Conclusion Levodopa was an effective method to improve visual fuction of youth amblyopia. United comprehensive treament as better than the comprehensive treatment. Don' t give up treat the youth of Ametropic Amblyoia.关键词
左旋多巴/屈光不正性弱视/综合疗法Key words
Levodopa/Ametropic amblyopia /Aomprehensive treatment引用本文复制引用
化志娟,胡敏,李亮亮..左旋多巴联合综合疗法治疗青少年屈光不正性弱视的疗效观察[J].临床眼科杂志,2013,21(2):146-149,4.基金项目
云南省科技厅社会发展计划基金资助重大项目(2009CA008) （2009CA008）
