国际眼科杂志2013，Vol.13Issue(5)：901-904,4.DOI:10.3980/j.issn.1672-5123.2013.05.17
RNA干扰技术在视网膜疾病治疗中的研究进展
RNA interference technology s research progress in the treatment of retinal disease
摘要
Abstract
RNA interference exists widely in animals, which can induce specific genetic sequence to silence by double -stranded RNA molecules at the mRNA level. As a kind of new methods of blocking gene expression, RNA interference technology has become increasingly mature and perfect, it has opened up a new approach of gene therapy. RNA interference can effectively prevent the formation of new vessels in retina, restrain the occurrence and development of the proliferative vitreous retinopathy, and induce apoptosis of retinoblastoma cells. The research progress of the RNA interference in the above retinopathy was summarized in this review.关键词
RNA干扰技术/视网膜新生血管疾病/增生性玻璃体视网膜病变/视网膜母细胞瘤Key words
RNA interference technology/ retinal newborn vascular disease/ proliferative vitroretinopathy/ retinoblastoma引用本文复制引用
李光辉,彭燕一..RNA干扰技术在视网膜疾病治疗中的研究进展[J].国际眼科杂志,2013,13(5):901-904,4.
