生物加工过程2013，Vol.11Issue(2)：30-36,7.DOI:10.3969/j.issn.1672-3678.2013.02.005
甾体生物转化技术研究的现状与进展
Current state and progress of biotransformation technology of steroid compounds
摘要
Abstract
Progress of biotransformation technology of steroid compounds was reviewed. The selection of steroid raw materials, selection and improvement of microbial strain and new technologies of biotransformation were discussed, including physical/chemical solubilizing of substrates, new transformation system and improvement of cell permeability. It is forecasted that the proportion of biotransformation technologies increased in the industrial production process of steroid hormone drugs.关键词
甾体/生物转化/药物中间体Key words
steroids/ biotransformation/ pharmaceutical intermediates分类
化学化工引用本文复制引用
许正宏,吴燕,李会,李恒,史劲松..甾体生物转化技术研究的现状与进展[J].生物加工过程,2013,11(2):30-36,7.基金项目
国家高技术研究发展计划(863计划)重大项目(2011AA02A211) （863计划）
国家自然科学基金(21206055) （21206055）
江苏省自然科学基金(BK2012127) （BK2012127）
