实用医学杂志2013，Vol.29Issue(6)：928-930,3.DOI:10.3969/j.issn.1006-5725.2013.06.026
青春期甲状腺功能亢进患者骨龄及骨代谢的特点分析
Characteristics of bone metabolism and bone age in adolescent patients with hyperthyroidism
摘要
Abstract
Objective To characterize the bone metabolism and bone age (BA) of adolescent patients with hyperthyroidism. Methods Serum free T3 (FT3), free T4, growth hormone, alkaline phosphatase, osteocalcin and BA in 60 adolescent patients with hyperthyroidism (hyperthyroidism group) and 50 healthy controls (control group) were detected. Results Compared to those in control group, BA was significantly backward, level of GH was lower, and bone metabolic markers were higher in hyperthyroid group. In hyperthyroid group, level of FT3 was positively correlated with BA backward, and was negatively correlated with GH level. As compared to those in patients with hyperthyroidism more than 1 year, BA backward difference and ALP level were significantly lower and GH level was higher in patients with hyperthyroidism less than 1 year. Conclusion BA of adolescent patients with hyperthyroidism was lagged. FT3 and BA backwark were more closely correlated. The longer the duration of hyperthyroidism, the more obvious BA backward was. The increased bone metabolism and GH reduction may be the important factors in causing BA backward.关键词
甲亢/青春期/骨龄/骨代谢/生长激素Key words
Hyperthyroidism/ Adolescent/ Bone age/ Bone metabolism/ Growth hormone引用本文复制引用
廖珂华,李妮,卢桂南..青春期甲状腺功能亢进患者骨龄及骨代谢的特点分析[J].实用医学杂志,2013,29(6):928-930,3.
