新医学2013，Vol.44Issue(4)：231-234,4.DOI:10.3969/g.issn.0253-9802.2013.04.004
早期饮食运动干预对妊娠糖尿病高危因素孕妇的胰岛素抵抗和妊娠预后的影响
Effect of early dietary advice and exercise intervention on insulin resistance and pregnancy outcome in pregnant women with high-risk factors for gestational diabetes mellitus
摘要
Abstract
Objective:To explore the effect of early dietary advice and exercise intervention (DAEI) on insulin resistance and pregnancy outcome in pregnant women with high -risk factors for gestational diabetes mellitus ( GDM ). Methods: One hundred and sisty pregnant women with high -risk factors for GDM were divided randomly into DAEI group (90 cases) and observation group (70 cases). The intervention started in 12 weeks after pregnancy and ended in final-phase of pregnancy (ends of 37 weeks). FBG, glucose in 2 h OGTT, insulin, insulin resistance index , and body weight changes were recorded. The incidence of GDM and pregnancy outcome were com -pared. Results: Compared with observation group , insulin, insulin resistance index decreased gradually in preg -nancy with higlnisk factors for GDM, and the incidence of GDM was lower in DAEI group , with significant difference (P < 0. 05). Complications of mothers and perinatals was lower in DAEI group than those in observation group , with significant difference ( P < 0. 05 ). Conclusion: Early DAEI could improve insulin resistance , reduce GDM incidence, and improve the pregnancy outcome and reduced complications of mothers and perinatals .关键词
妊娠糖尿病/高危因素/饮食运动干预/胰岛素抵抗,妊娠结局Key words
Gestational diabetes mellitus /High -risk factors /Dietary advice and exercise intervention /Insu-lin resistance /Pregnancy outcome引用本文复制引用
陈勇霞,田耕,苗润,萧慧娟..早期饮食运动干预对妊娠糖尿病高危因素孕妇的胰岛素抵抗和妊娠预后的影响[J].新医学,2013,44(4):231-234,4.基金项目
广东省医学研究基金资助(A2012258) （A2012258）
