新医学2013，Vol.44Issue(4)：250-252,3.DOI:10.3969/g.issn.0253-9802.2013.04.009
吉西他滨联合奈达铂治疗晚期非小细胞肺癌的近期疗效观察
Gemcitabine combined with Nedaplatin in the treatment of advanced non-small cell lung cancer
林尤恩 1王晓芬 1王春冰 1许宏伟 1邢佳鹏1
作者信息
摘要
Abstract
Objective:To observe the efficacy and the side -effects of gemcitabine ( GEM) combined with nedaplatin (NDP) on advanced non-small cell lung cancer (NSCLC). Methods; 24 patients with NSCLC were treated with gemcitabine (GEM 1 000 mg/m2, ivdrip, d1, d8) plus nedaplatin (NDP 100 mg/m2, ivdrip, d1, every 3 weeks) , each 6 cycles. Results: 10 patients out of 24 were partial response , 6 patients were stable , 8 patients were progressive. The RR was 41. 7% (10/24). Disease control rate was 66. 7%. The median time to progress was 3. 2 months and the median survivaltime was 7. 9 months. The main side-effects were fairly, including myelosuppression , partial peripheral neurotoxicity , nausea and vomitin. Conclusion: Gemcitabine combined with nedaplatin is effective and well tolerated in patients with advanced non -small cell lung cancer.关键词
吉西他滨/奈达铂/晚期非小细胞肺癌/化学治疗Key words
Gemcitabine/Nedaplatin/Non-small cell lung cancer/Chemotherapy引用本文复制引用
林尤恩,王晓芬,王春冰,许宏伟,邢佳鹏..吉西他滨联合奈达铂治疗晚期非小细胞肺癌的近期疗效观察[J].新医学,2013,44(4):250-252,3.
