中国脑血管病杂志2013，Vol.10Issue(4)：178-181,4.DOI:10.3969/j.issn.1672-5921.2013.04.003
应用单光子发射断层显像评价合并大脑后动脉病变的烟雾病患者脑血流灌注
Evaluation of cerebral perfusion in moyamoya diseased patients with posterior cerebral artery lesions by single photon emission tomography examination
摘要
Abstract
Objective To analyze the abnormal cerebral blood flow perfusion in moyamoya diseased patients with posterior cerebral artery ( PCA) lesions. Methods A total of 27 moyamoya diseased patients with posterior cerebral artery lesions were enrolled in the study. According to the digital subtract an-giography (DSA) results, the Suzuki s stages of 27 patients ( 54 hemispheres) were determined and the PCA grading in all the 27 patients were identified. All the patients accepted single photon emission tomography ( SPECT) examination, and the mean value of three or four regions of interest was calculated in five regions ( frontal, parietal, temporal, and occipital lobes and basal ganglia). The cerebral - to - cerebellar activity ratio was calculated by dividing the count in these regions by that in the cerebellar hemisphere to assess the rCBF. The effects of the lesion grading of PCA, different Suzuk's grades on rCBF ratio were determined. Results ① With the increasing of PCA severity, the rCBF in frontal lobe, parietal lobe, temporal lobe, occipital lobe, and basal ganglia decreased gradually. There were significant differences ( all P<0.05).The rCBF ratio value (74 ±6) of the slight PCA lesions in the parietal lobe was higher than that of moderate lesions (63 ± 9) or severe lesions (60 ± 17). There were significant differences. The rCBF ratio value (72 ± 7 ) of slight PCA lesions in the occipital lobe was higher than that of the moderate lesions (65 ±9) and severe lesions (60 ± 15). There were significant differences. ②There were no significant differences in the rCBF ratio comparisons of frontal lobe, parietal lobe, temporal lobe, occipital lobe, and basal ganglia (P > 0.05). Conclusion The rCBF ratio in each lobe decreases with the severity of PCA lesions, but they are not associated with the severity of the Suzuki's stage. Posterior circulation lesion is an important factor of affecting the cerebral perfusion level in patients with moyamoya disease.关键词
烟雾病/脑血流灌注/后循环Key words
Moyamoya disease/ Cerebral perfusion/ Posterior circulation引用本文复制引用
王莉,段炼,杨伟中,龙亚红,暴向阳,赵峰,咸鹏..应用单光子发射断层显像评价合并大脑后动脉病变的烟雾病患者脑血流灌注[J].中国脑血管病杂志,2013,10(4):178-181,4.基金项目
国家自然科学基金面上项目(81171083) （81171083）
解放军第三○七医院创新科研基金重点项目(ZD-2012-04) （ZD-2012-04）
