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Muc2和DCN基因敲除小鼠食子现象的初步研究

李巍 贺国洋

中国比较医学杂志2013,Vol.23Issue(4):28-30,3.
中国比较医学杂志2013,Vol.23Issue(4):28-30,3.DOI:10.3969.j.issn.1671.7856.2013.004.007

Muc2和DCN基因敲除小鼠食子现象的初步研究

Preliminary study of kronismus in Muc2 and DCN gene knockout mice

李巍 1贺国洋1

作者信息

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摘要

Abstract

Objective To explore the differences in kronismus of Muc2 and DCN gene knockout mice. Methods Knockout homozygote males and females ( Muc2 -/ - ,DCN -/ - ) mice were mated respectively according to 1 :1 or 1 ;2 ratio. The average litter size of 1 - 3 generations, parity interval time, and kronismus in Muc2 and DCN gene knockout mice were observed. Results An average litter size of Muc2 gene knockout mice was 5.80 ±0.95. The average birth interval time was 42. 29 ±2. 28 days. The average DCN knockout mice seed production was 3. 85 ±0. 76, and the average birth interval time was 24. 86 ± 10. 42 days. There were significant differences between Muc2 and DCN gene knockout mice in the average litter size, parity interval time, and kronismus. Conclusions The reproductive performance of the two groups of gene knockout mice are different, indicating that Muc2 and DCN genes may be associated with reproductive function.

关键词

Muc2/DCN基因敲除/食子现象

Key words

Muc2/ DCN/ Gene knockout mice/ Kronismus

分类

医药卫生

引用本文复制引用

李巍,贺国洋..Muc2和DCN基因敲除小鼠食子现象的初步研究[J].中国比较医学杂志,2013,23(4):28-30,3.

中国比较医学杂志

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1671-7856

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