中国医科大学学报2013，Vol.42Issue(4)：351-354,4.
PET-CT在检测早期子宫颈癌淋巴结转移中的诊断价值
Diagnostic Value of PET-CT in Detection of Lymph Node Metastasis in Early-stage Cervical Carcinoma
摘要
Abstract
Objective To determine the sensitivity and specificity of PET in diagnosis of lymph node metastasis in patients with early-stage cervical carcinoma. Methods Clinical data of all patients with stage Ⅰ A- Ⅱ A cervical carcinoma who underwent PET before surgery between Oct 2007 and Oct 2012 were retrospectively reviewed. The histologic size of the regional lymph nodes and lymph node pathology was compared and correlated. Results Totally 102 patients were recruited for the current study. Pelvic lymph node metastases were present in 28.4% of the patients and detected by PET with a sensitivity of 37.9%,a specificity of 91.8%,a positive predictive value (PPV) of 66.7%, and a negative predictive value (NPV) of 79.8%. Paraaortic lymph node disease was present in 11.1% of patients and detected by PET with a sensitivity of 40.0%,a specificity of 97.5%,a PPV of 66.7%,and an NPV of 92.9%. There was no statistical difference of mean histologic size of the involved lymph nodes between the PET-positive pelvic lymph nodes and the PET-negative pelvic lymph nodes (15.6 mm vs. 13.7 mm;P = 0.256). Conclusion PET-CT has a low sensitivity but a high specificity for diagnosis of lymph node metastasis in patients with early-stage cervical carcinoma.关键词
子宫颈肿瘤/淋巴转移/正电子发射断层显像术/体层摄影术,螺旋计算机Key words
cervix neoplasms/ lymphatic metastasis/ positron-emission tomography/ tomography/ spiral computed分类
医药卫生引用本文复制引用
陈英汉,王丹波,李雅男,矫亮,孙小单..PET-CT在检测早期子宫颈癌淋巴结转移中的诊断价值[J].中国医科大学学报,2013,42(4):351-354,4.基金项目
国家自然科学基金资助项目(81070467) （81070467）
