南方医科大学学报2013，Vol.33Issue(3)：448-450,3.DOI:10.3969/j.issn.1673-4254.2013.03.30
计算机辅助精液分析精子运动参数在体外受精中的应用
Computer-assisted sperm analysis for assessing sperm mobility parameters in in vitro fertilization
摘要
Abstract
Objective To evaluate the association of sperm mobility parameters assessed by computer-assisted sperm analysis (CASA) with the rates of normal fertilization, oocyte cleavage and excellent embryos in in vitro fertilization (IVF) cycles. Methods A total of 288 infertile women undergoing IVF cycles patients were divided into two groups according to the normal fertilization rate (≥50% and <50%), cleavage rate (≥90% and <90%), or excellent embryo rates (≥50% and <50%). The means of the sperm motility parameters analyzed by CASA twice before oocyte retrieval were recorded and analyzed using t-test in relation to the rates of normal fertilization, cleavage and excellent embryos in IVF cycles. Results The mean curvilinear velocity (VCL), average path velocity (VAP), and amplitude of lateral head displacement (ALH) were significantly higher in women with a normal fertilization rate of ≥50% than in those with a normal fertilization rate of <50% (P<0.05). Women with an oocyte cleavage rate of ≥90% had significantly higher VCL and VAP than those with a cleavage rate of <90% (P<0.05). The VCL, straight line velocity (VSL), VAP, linearity, straightness, wobble coefficient, ALH, or beat-cross frequency showed no significant differences between women with excellent embryo rates of ≥50% and <50% (P>0.05). Conclusion The sperm motility parameters assessed using CASA are associated with normal fertilization and oocyte cleavage rates but not with excellent embryo rate in IVF cycles.关键词
计算机辅助精液分析/试管婴儿/正常受精率/卵裂率/优良胚胎形成率Key words
computer-assisted sperm analysis/ in vitro fertilization/ normal fertilization rate/ cleavage rate/ excellent embryo rate引用本文复制引用
袁平庆,张哲欢,罗琛,全松,褚庆军,赵善超..计算机辅助精液分析精子运动参数在体外受精中的应用[J].南方医科大学学报,2013,33(3):448-450,3.基金项目
广东省自然科学基金(10451051501005741) （10451051501005741）
广东省人口和计划生育委员会资助科研项目(2010240) （2010240）
