肝胆胰外科杂志2013，Vol.25Issue(2)：116-118,121,4.
早期肠内营养对重症急性胰腺炎患者血清CRP及T淋巴细胞亚群的影响
Effect of early enteral nutrition for severe acute pancreatitis patiens on serum C-reactive protein and T lymphocyte subsets
摘要
Abstract
Objective To study the effect of early enteral nutrition (EEN) for severe acute pancreatitis (SAP) patients on serum C-reactive protein (CRP) and T lymphocyte subsets. Methods Forty-five SAP patients were randomly divided into the experimental group (22 cases) and the control group (23 cases). The experimental group was treated with EEN. The control group were treated with early parenteral nutrition (PN), and EN was given after gastrointestinal function restored (usually after admission 5 to 7 d). On the day 1, 5, 7 and 11 after admission, the patients of two groups were tested serum CRP and T lymphocyte subsets (CD3, CD4+, CD47CD8+ ratio). Results Three patients were excluded experiment, and the other 42 cases were cured. The average hospitaliza-tion days and costs in experimental group were lower than that in control group (P<0.05). The serum levels of CRP and T lymphocyte subsets, on the first day, were not statistically significant differences between two groups (P>0.05). On the 5th, 7th and 11th hospitalization day, the serum CRP level was lower in experimental group than that in control group (P<0.05), and the T lymphocyte subsets (CD3, CD4+, CD4+/CD8+ ratio) levels were higher in experimental group than those in control group (P<0.05). Conclusion This experiment shows that, by comparing experimental group with control group, the treatment for SAP patients with EEN is better in reducing inflammation on the acute reaction period and better in improving immune function.关键词
重症急性胰腺炎/肠内营养/C反应蛋白/T淋巴细胞亚群Key words
severe acute pancreatitis/ enteral nutrition/ C-reactive protein/ T lymphocyte subsets分类
医药卫生引用本文复制引用
苗祥,昝建宝,宋康颉,胡明玉,徐爱忠..早期肠内营养对重症急性胰腺炎患者血清CRP及T淋巴细胞亚群的影响[J].肝胆胰外科杂志,2013,25(2):116-118,121,4.基金项目
安徽省教育厅高校省级自然科学研究项目(KJ2011Z209). （KJ2011Z209）
